After connecting your store you will be presented with the store settings, these settings allow you to change & interact with the following:

Decide what is the fixed minimum profit you would like to make.

Decide what is the minimum percentage of profit you would like to make.

Change the way the profit calculator & monitor will round your product final price.

The defaults that are set for you are the minimum advised by the community:

for eBay stores - 3$ fixed minimum profit & 10% percentage of minimum profit

The monitor will take the higher of the two.

You can also change these settings afterward by going to your account settings -> store settings, and choosing your store.